

Classification: Selective Estrogen Receptor Modulator (SERM)
Active substance: Enclomiphene
Manufacturer: Dragon Pharma
Form/Strength: Tablet, 25 mg/tablet
Pack size: 100 tablets
Route: Oral
For bodybuilders and athletes seeking advanced post-cycle therapy solutions, Dragon Pharma Enclomiphene represents the next generation of Selective Estrogen Receptor Modulators (SERMs). Containing 25mg of pure Enclomiphene Citrate per tablet, this cutting-edge compound offers targeted estrogen modulation without the estrogenic activity associated with traditional Clomid. As the more effective isomer of Clomiphene, Enclomiphene provides superior stimulation of natural testosterone production, making it an essential component of modern PCT protocols and testosterone optimization strategies. Sourced from the reputable Dragon Pharma laboratory, this product delivers pharmaceutical-grade quality with consistent dosing accuracy.
Enclomiphene works through a sophisticated mechanism as a selective estrogen receptor modulator (SERM). Unlike its counterpart zuclomiphene, Enclomiphene possesses pure anti-estrogenic properties without intrinsic estrogenic activity. Its primary action occurs at the hypothalamic level, where it competitively binds to estrogen receptors, effectively blocking estrogen's negative feedback on the hypothalamus.
This blockade tricks the body into perceiving low estrogen levels, triggering a cascade of hormonal responses: increased Gonadotropin-Releasing Hormone (GnRH) secretion from the hypothalamus, followed by elevated Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) production from the pituitary gland. These gonadotropins then stimulate the testes to produce more testosterone naturally. According to research published by the National Institutes of Health, enclomiphene demonstrates significant efficacy in increasing testosterone levels while maintaining favorable safety profiles compared to traditional testosterone therapies.
Proper Enclomiphene dosing depends on your specific goals, whether for post-cycle therapy or testosterone optimization. For most applications, the optimal dosage ranges between 12.5mg to 25mg daily.
For Post-Cycle Therapy (PCT): Begin with 25mg daily for 2-3 weeks, then reduce to 12.5mg daily for an additional 2-3 weeks. This protocol typically starts 2-3 weeks after your last injection of long-ester compounds. For testosterone optimization or "bridge" cycles: 12.5mg daily is often sufficient to maintain elevated natural testosterone production. Some users benefit from cycling 3-4 weeks on followed by 1-2 weeks off. Enclomiphene is typically taken once daily, preferably at the same time each day, with or without food. The 25mg tablet allows for easy splitting to achieve precise 12.5mg doses when needed.
Enclomiphene's versatility makes it valuable in various scenarios beyond traditional PCT. Its ability to stimulate natural testosterone production creates opportunities for innovative cycle designs and recovery protocols.
Enclomiphene is generally well-tolerated with a favorable side effect profile compared to traditional clomiphene citrate, primarily because it lacks the estrogenic zuclomiphene isomer. However, some users may experience side effects, particularly at higher doses.
Potential side effects may include:
These effects are typically dose-dependent and diminish with dosage reduction or discontinuation. Regulatory guidance on this Dragon Pharma SERM Enclomiphene emphasizes its generally favorable safety profile while recommending regular monitoring during extended use. To minimize risks, always use the lowest effective dose and consider periodic breaks during long-term use.
Understanding the differences between Enclomiphene and traditional Clomid (clomiphene citrate) is crucial for making informed decisions about your PCT strategy. While both compounds are SERMs, Enclomiphene offers distinct advantages as the purified trans-isomer of clomiphene.
Traditional clomiphene contains both enclomiphene (trans-clomiphene) and zuclomiphene (cis-clomiphene) in approximately a 3:2 ratio. The zuclomiphene component has estrogenic activity and a much longer half-life (weeks compared to hours for enclomiphene), which can lead to estrogenic side effects and prolonged receptor binding. Enclomiphene, being free from zuclomiphene, provides more predictable anti-estrogenic effects without the estrogenic activity, resulting in cleaner stimulation of gonadotropin secretion and fewer visual side effects.
In the evolving landscape of performance enhancement and hormonal optimization, product quality and consistency are paramount. Dragon Pharma has established itself as a trusted manufacturer known for precise dosing, product purity, and innovative formulations. When you purchase Dragon Pharma Enclomiphene, you're investing in a cutting-edge compound that represents the future of SERM technology. The 25mg tablet formulation allows for flexible dosing strategies, while the 100-tablet pack provides sufficient quantity for complete PCT protocols or extended testosterone optimization cycles. Each batch undergoes rigorous quality control to ensure accurate dosing and product purity—essential factors for a compound where precise estrogen modulation is critical for success.
Enclomiphene is the purified trans-isomer of clomiphene, while traditional Clomid contains both enclomiphene and zuclomiphene isomers. Zuclomiphene has estrogenic properties and a longer half-life, which can cause more side effects. Enclomiphene provides cleaner estrogen receptor blockade without intrinsic estrogenic activity, resulting in more effective testosterone stimulation with fewer visual disturbances and side effects.
Yes, some advanced users implement low-dose Enclomiphene (12.5mg EOD) during cycles to maintain some endogenous testosterone production, particularly during oral-only or SARM cycles. This "testosterone base" approach can help preserve natural function and potentially ease post-cycle recovery. However, during strong suppressive cycles with injectables, its effectiveness may be limited due to the profound shutdown of the HPTA axis.
You can expect to see initial changes in hormone levels within 3-5 days of starting Enclomiphene, with significant increases in LH and FSH within 1-2 weeks. Testosterone levels typically show substantial improvement within 2-3 weeks, though full recovery of natural production after a suppressive cycle may take 4-6 weeks. The speed of response can vary based on individual factors, the extent of previous suppression, and dosage used.
While Enclomiphene has been studied for female infertility treatment, it is not recommended for female performance enhancement without medical supervision. The compound can significantly impact the menstrual cycle and hormonal balance in women, potentially causing unpredictable effects. Women should consult with an endocrinologist before considering any SERM therapy.
A standard Enclomiphene PCT protocol lasts 4-6 weeks, typically starting with 25mg daily for the first 2-3 weeks, then reducing to 12.5mg daily for the remaining duration. For more suppressive cycles, some users extend to 6-8 weeks. The optimal duration depends on the length and intensity of your previous cycle, with longer and more suppressive cycles requiring longer PCT. Blood work after PCT completion is recommended to confirm successful recovery.
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